Friday, June 02, 2006

4 Ts of HIT

Friday June 2, 2006
4 Ts of HIT

Continuing our theme of Heparin-Induced Thrombocytopenia (HIT) from yesterday, lets talk today about "4 Ts" of HIT.

Thrombocytopenia - more than 50% fall

Timing of platelet count fall - Days 5 to 10, or less than/= 1 day if heparin exposure within past 30 days

Thrombosis or other sequelae - Proven thrombosis, skin necrosis, or, after heparin bolus, acute systemic reaction

Other cause for thrombocytopenia - None

American Society of Hematology has developed a full HIT score which can be seen by clicking here. 1

References: click to get abstract/article

When Heparins Promote Thrombosis - Review of Heparin-Induced Thrombocytopenia - Circulation. 2005;111:2671-2683